Groups

Negative control

Low-dose group

Middle-dose group

High-dose group

After feeding samples for 3 months

(n = 16)

ALT (U/L)

41.9 ± 5.8

45.0 ± 8.0

41.6 ± 6.0

43.9 ± 7.7

AST (U/L)

100.3 ± 8.1

106.3 ± 10.5

101.2 ± 11.3

103.1 ± 10.3

ALP (U/L)

101.1 ± 18.0

105.8 ± 22.9

101.4 ± 16.9

95.4 ± 13.4

TbiL (mmol/L)

1.781 ± 0.811

2.007 ± 0.844

2.036 ± 0.966

1.783 ± 1.252

BUN (mmol/L)

5.786 ± 0.381

6.024 ± 0.409

5.854 ± 0.492

6.041 ± 0.437

CREA (mmol/L)

26.08 ± 1.70

28.79 ± 3.14^**

30.80 ± 3.21^**

30.80 ± 3.79^**

GLU (mmol/L)

8.228 ± 0.614

8.087 ± 0.407

8.012 ± 0.610

7.775 ± 0.771

TP (g/L)

62.02 ± 1.97

62.46 ± 2.02

61.00 ± 2.53

60.65 ± 2.46

ALB (g/L)

33.10 ± 2.30

33.05 ± 2.16

32.85 ± 2.51

32.31 ± 1.80

TG (mmol/L)

0.540 ± 0.100

0.567 ± 0.095

0.539 ± 0.125

0.555 ± 0.068

CHOL (mmol/L)

1.805 ± 0.276

1.906 ± 0.220

1.977 ± 0.210

1.821 ± 0.166

After recovery for 2 weeks (n = 8)

ALT (U/L)

36.0 ± 5.7

36.1 ± 6.3

37.4 ± 5.9

35.0 ± 4.7

AST (U/L)

106.6 ± 6.2

109.9 ± 7.2

108.3 ± 11.9

107.0 ± 3.6

ALP (U/L)

86.0 ± 12.2

80.0 ± 18.7

77.4 ± 20.3

78.6 ± 14.6

TbiL (mmol/L)

1.530 ± 0.989

2.058 ± 0.652

1.976 ± 0.833

1.515 ± 1.089

BUN (mmol/L)

5.956 ± 0.563

6.015 ± 0.461

6.260 ± 0.548

6.334 ± 0.320

CREA (mmol/L)

30.10 ± 4.54

31.68 ± 4.22

37.33 ± 4.57^**

37.01 ± 3.50^**

GLU (mmol/L)

8.111 ± 0.332

7.968 ± 0.461

8.445 ± 0.801

8.166 ± 0.778

TP (g/L)

59.90 ± 3.14

60.59 ± 4.46

60.03 ± 2.69

59.20 ± 3.37

ALB (g/L)

32.91 ± 1.80

33.09 ± 2.30

33.00 ± 1.62

32.19 ± 1.61

TG (mmol/L)

0.514 ± 0.072

0.535 ± 0.056

0.535 ± 0.092

0.599 ± 0.106

CHOL (mmol/L)

1.879 ± 0.331

2.001 ± 0.290

1.973 ± 0.169

1.840 ± 0.130